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Studies by a team of researchers at PLIVA and the University of Pcs in Hungary found a similar protective effect when they tested pieces of the peptide in freshly isolated rat stomach cells

NOX-derived ROS stimulate the transcription of pro-inflammatory genes via factors such as NF-B (9092) or NFAT (93)

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EMBO J 13(12):28702875 Higashimoto M, Isoyama N, Ishibashi S, Inoue M, Takiguchi M, Suzuki S, Ohnishi Y, Sato M (2009) Tissue-dependent preventive effect of metallothionein against DNA damage in dyslipidemic mice under repeated stresses of fasting or restraint

BPC157 was added at concentrations of 5, 10, 20, and 40 g ml-1 for the indicated periods

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