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2 Overview of idiopathic pulmonary fibrosis 2.1 Characterization of idiopathic pulmonary fibrosis Histologically, IPF is characterized by UIP patterning, in which the lung interstitiuma band-like tissue supporting alveoliundergoes ECM deposition and architectural disorganization ( 2.2 Pathogenesis and therapeutic targets of idiopathic pulmonary fibrosis 2.2.1 Alveolar epithelial cell injury and abnormal repair The etiology and pathogenesis of PF, particularly IPF, are largely undetermined, but notable advancements and consensus have been achieved in the field
Nat Rev Mol Cell Biol 2003;4:91525

Previously, we constructed three compatible plasmids into which each of egt genes ( egtB , egtC , egtD , egtE ) derived from M