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An increasing number of studies are showing that TNF- and IL-6 are the primary inflammatory cytokines implicated in cancer cachexia [7, 9], and these have emerged as critical factors related to the loss of muscle mass

In addition, smokers accumulate toxic levels of another metal element, cadmium, which accumulates in testicular tissue and further adds to oxidant stress

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Clinical Applications Flanagan et al
Effects of ketogenic diet on cognitive functions of mice fed high-fat-high-cholesterol diet

Wilson AC, Dugger BN, Dickson DW, Wang D-S
