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For in vitro experiments, comparative analyses between different experimental groups were performed using t-student test and one-way ANOVA with Tukey post hoc tests for intergroup comparisons unless otherwise stated

Remove particulates from the concentrated sample using a 0.22 m filter unit, or centrifuge the sample at 4,000 g for 20 min

It has been studied as monotherapy and, more commonly, in combination with GLP-1 receptor agonists (e.g., semaglutide) to target complementary mechanisms involved in weight regulation

doi: 10.1073/pnas.91.16.7491

To date, of participants in our study (n = 55) with histories of magnetic resonance imaging contrast agent exposure (10 days15.5 years after the latest administration), 70% have serum gadolinium concentrations less than 640 p.m