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Urinary organic acid analyses were performed on a gas chromatography-mass spectrometry (GC-MS) system

Considering that ALA could effectively stabilize hepatic Fe 2+ expression (Figure 1), and depress both levels of ferroptotic (Figure 2) and pro-apoptotic signaling (Figure 6), dietary supplementation with ALA may thus serve as a useful and practical way to prevent, or further counteract the CSD-induced liver injury and metabolic deficiency

Pharmacokinetic data obtained by measuring NAC levels in aqueous humor throughout the treatment period are informative because they demonstrate that good intraocular levels of NAC are obtained after oral dosing

[DOI] [PubMed] [Google Scholar] 99.Pelosi L, Giacinti C, Nardis C, et al

This is in contrast to class I GRXs from poplar, where glutathionylation occurs at the same redox potential as disulfide formation 33

Increased expression of efflux transporters might be an adaptive change to stop accumulation of toxic metabolites in cells and to prevent additional liver damage