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Reduced choline-containing compounds in cortical regions is a consistent, transdiagnostic abnormality in AnxDs

Vitamin B12 is an essential nutrient that is essential for keeping the bodys nerve and blood cells healthy.

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It also supports the detoxification process and promotes liver and immune system health

This review integrates current evidence on how brain peptides contribute to AD pathophysiology, summarizes recent progress in peptide-based therapeutic strategies and delivery platforms, and critically examines the remaining barriers to clinical translation, including bloodbrain barrier penetration, metabolic stability, off-target effects, and the need for biomarker-guided patient stratification