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Remarkably, the TSS pathway is compensatively activated when the extracellular source of cystine is restricted or under extreme oxidative stress conditions
References 1.Booth J., Boyland E., Sims P

10.1515/znc-2005-3-403 Z

These studies suggest a potential for NAC administration as an adjunct therapeutic in MDD

J Nucleic Acids Res 46:257263 Barcellos MP, Santos CB, Federico LB, Almeida PF, da Silva CH, Taft CA (2019) Pharmacophore and structure-based drug design, molecular dynamics and admet/tox studies to design novel potential pad4 inhibitors

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