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Cartilage-focused research, including work summarized in the NIH PubMed database, explored chondrocyte effects relevant to joint repair models and suggested a potential adjunct role alongside established biologics

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In humans, direct ANP infusion at maximal dose increases lipolysis greater than 10-fold (114) and can decreases blood pressure, and increases post-prandial lipid oxidation and energy expenditure (111), suggesting therapeutic benefits of ANP treatment are possible in man

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