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Availability of data and materials N/A Abbreviations ALCAR: Acetyl-L-carnitine ANG: Angiogenin BPH: Benign prostatic hyperplasia CCL2: C-C Motif Chemokine Ligand 2 CCR2: C-C chemokine receptor type 2 CM: Conditioned media CXCL12: C-X-C Motif Chemokine Ligand 12 CXCL8: C-X-C Motif Chemokine Ligand 12 CXCR1: C-X-C chemokine receptor type 1 CXCR2: C-X-C chemokine receptor type 2 CXCR4: C-X-C chemokine receptor type 4 DAPI: 4,6-diamidino-2-phenylindole EBM: Endothelial basal medium EGM: Endothelial growth medium FACS: Fluorescence activated cell sorting FBS: Foetal bovine serum FC: Flow cytometry FSC: Forward-scattered light ICAM-1: Intercellular adhesion molecule 1 IL-6: Interleukin-6 MCP-1: Monocyte chemoattractant protein 1 NFB: Nuclear factor kappa-light-chain-enhancer of activated B cells PBMCs: Peripheral blood mononuclear cells PCa: Prostate cancer SDF-1: Stem-derived facrior-1 SSC: Side-scattered light VEGF: Vascular endothelial growth factor VEGFR: Vascular endothelial growth factor receptor References Jaiswal S, Sarmad R, Arora S, Dasaraju R, Sarmad K

3a) 19,60,61,62 , led to an increase in lipid droplets and a slight but significant lifespan extension (Fig

Fordeler: Underskes for sttte til kt melaninproduksjon og pigmentering Kan pvirke hudrespons p UV-eksponering Forskning indikerer effekt p appetittregulering Kan ha innvirkning p energiniv og metabolsk signalering Brukes i studier relatert til melanokortin-systemet Melanotan II benyttes hovedsakelig i forskningssammenheng og er kjent for sin sterke affinitet til melanokortinreseptorer.

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These parental Cas9 lines also express a GL2 -targeting sgRNA from the AtU6 promoter