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Preclinical research demonstrated that NNMT inhibition with 5-Amino-1MQ reduced white adipose tissue mass by ~35% , shrank adipocyte size by 30-40%, and lowered plasma cholesterol by ~30% all without affecting food intake

While it has been in research for over 20 years, it has recently gained a second life thanks to the massive public interest in peptide therapy and the rise of GLP-1 medications.

While methylcobalamin contains a methyl group, cyanocobalamin contains a cyanide molecule
