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Because it does not raise IGF-1 or affect blood sugar, the metabolic risks associated with HGH or insulin-affecting agents do not apply

In fact, vitamin B12 deficiency is a known contributor to neural tube defects
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20 Systematic reviews: Oral vitamin B 12 replacement for the treatment of pernicious anemia 21 Relevant articles were identified by PubMed search from January 1, 1980 to March 31, 2016, focusing on patients with pernicious anemia

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