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Gently massage: Use your fingertips to massage the serum into your skin in upward circular motions

Once reconstituted with sterile or bacteriostatic water, the solution should be stored refrigerated and used within the recommended timeframe according to laboratory handling guidelines

Keep the lid tightly closed and avoid contaminating the cream with fingers (use a small spatula)

In this Review, the authors examine the contribution of abnormalities in the glutamatergic system to the impairments in neural plasticity that are observed in patients with mood disorders, and how this knowledge can be applied to the development of antidepressants with more rapid and sustained effects.