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More patients receiving tirzepatide discontinued treatment due to GI adverse reactions than patients receiving placebo during all clinical trials

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It is often seen alongside: Ehlers-Danlos Syndrome (EDS) POTS (Postural Orthostatic Tachycardia Syndrome) Small Intestinal Bacterial Overgrowth (SIBO) Mold illness (CIRS) Lyme disease and co-infections Long COVID or post-viral syndromes Autoimmune disease (e.g., Hashimotos, lupus) Histamine intolerance Diagnosing MCAS MCAS is a clinical diagnosis, supported by lab testing

Intestinal-Inflammation Research: BPC-157 is studied in preclinical models of inflammatory gastrointestinal conditions

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Patchy loss or cycles of flare and recovery
