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In high concentrations, however, some amino acids can be toxic to certain cells, as observed with Glu toxicity in neurons [45] and Cys toxicity in many types of cells, including neurons and hepatocytes

The only US FDA-approved pharmacological therapy is riluzole, which could prolong survival by ~2 months in ALS patients

Iron-induced lipid peroxidation is a primary trigger of NAFLD, with GPX4 serving as a key regulator that mediates lipid peroxidation-induced ferroptosis

Candidate's thesis: enhancing intrinsic cochlear stress defenses to reduce noise-induced hearing loss

Single-molecule spatial transcriptomics of human thoracic aortic aneurysms uncovers calcification-related CARTPT -expressing smooth muscle cells

Retrieved April 20, 2018