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If cloudiness persists, let the vial rest for 5-10 minutes and swirl again

et al., 2015), thus inhibiting cisplatin-induced cytotoxicity

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In some embodiments, the otic formulation or composition comprises between about 0.1% to about 30% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

For instance, under inflammatory conditions microglia increase their secretion of ApoE whereas astrocytes do not, and microglia release a single ApoE species whereas astrocytes release two that are under different states of glycosylation (Lanfranco et al., 2021)

Forte D, Krause DS, Andreeff M , Bonnet D, Mndez-Ferrer S