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Baseline oxidative stress markers such as malondialdehyde (MDA), 8-hydroxy-2-deoxyguanosine (8-OHdG), and antioxidant enzyme activity predict responsiveness

Epub 2015 Apr 30

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Mice undergoing in vivo reprogramming were found to become depleted in B 12 and show signs of methionine starvation while supplementing reprogramming mice and cells with B 12 increased reprogramming efficiency, indicating a cell-intrinsic effect

If you dont get enough vitamin B-6, you may develop symptoms like dry hair, cracked lips, and fatigue