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Description
METH stimulates the release of excess glutamate from neurons while inhibiting its uptake by astrocytes, leading to the overactivation of NMDARs ( tThe excitotoxicity induced by METH also triggers neuroinflammation and amplifies its neurotoxic effects
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Lidocaine Continuous Subcutaneous Infusion for Neuropathic Pain in Hospice Patients: Safety and Efficacy

E.et al (1982)
The most effective approaches include: Strength training: builds muscle, which improves insulin sensitivity and increases metabolic rate Cardio: especially brisk walking, cycling, or swimming, helps burn stored fat HIIT (high-intensity interval training): short bursts of intense effort followed by rest can be especially effective Even moderate, consistent activity (like 30 minutes of walking most days) can significantly lower visceral fat over time

Lancet 2001;358:17549.ArticlePubMed 33