glutathione peroxidase 1 structure GPX1 and Its Dichotomous Roles in Cancer Glutathione peroxidase 3 - Wikipedia

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Notably, loss-of-function mutations in ABCG2 (e.g., Q141K) impair intestinal urate excretion, thereby significantly increasing the risk of gout (Kawaguchi et al., 2021

Oncologic and Functional Hazards of Obesity Among Patients With Locally Advanced Rectal Cancer Following Neoadjuvant Chemoradiation Therapy

However, an imbalance between ROS production and antioxidant defense mechanisms can lead to oxidative stress, a pathological state linked to diseases like cancer and neurodegeneration [9]

EMT, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer