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The ZIP family facilitates the influx of zinc into the cytosol from either the extracellular space or intracellular organelles, whereas the ZnT family exports zinc from the cytosol to organelles or out of the cell 15,30

Indeed, studies in both tumor cell lines and animals confirmed that a therapeutic advantage was obtainable with combinations of ethacrynic acid and alkylating agents (Tew et al , 1988

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Int J Tuberc Lung Dis