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5-Amino-1MQ is a selective small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) an enzyme implicated in adipocyte energy storage, NAD+ metabolism, and one-carbon metabolic signalling

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[104] [105] Deficiency does not develop if dietary intake of vitamin B 12 is adequate or prophylactic B 12 supplementation is given

[DOI] [PMC free article] [PubMed] [Google Scholar] 125.Mumford S.L., Schisterman E.F., Siega-Riz A.M., Browne R.W., Gaskins A.J., Trevisan M., Steiner A.Z., Daniels J.L., Zhang C., Perkins N.J., et al