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By up-regulation of inflammatory cytokine genes and enhanced BBB permeability, reactive astrocytes are frequently engaged in processes of neurodegeneration and neuroinflammation

FTY720 requires vitamin B12-TCN2-CD320 signaling in astrocytes to reduce disease in an animal model of multiple sclerosis by Jerold Chun et al

doi: 10.1126/science.1209038

10.1172/JCI144201 J
Blasi, M
