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10.1186/s12943-022-01597-7 [DOI] [PMC free article] [PubMed] [Google Scholar] Hou W., Xie Y., Song X., Sun X., Lotze M
A potential cardiovascular benefit was found because of the action of CNX-010-49 on plasminogen activator inhibitor-1 (PAI-1), interleukin-6 (IL-6), and fetuin-A (221)

However, if your needs are higher due to diet or absorption issues, a standalone B12 supplement may be advised

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