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This study revealed that the TYK2 FERMSH2 domains form a clover shaped structure with the SH2 being the forth leaf

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J Biol Rhythms

doi: 10.1016/j.molcel.2019.10.023 144 OuyangWWangSYanDWuJZhangYLiWet al

Moderate responders form the largest group, experiencing significant improvement between weeks 3-6

Originally developed to treat type 2 diabetes, it has shown promise in helping individuals lose weight
