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In a phase 2 substudy that included participants with hepatic fat content 10%, 48-week administration of GLP-3 resulted in a robust, dose-dependent reduction in liver fat

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In mammals, CAC can accept acylcarnitines with acyl chains of various lengths from 2 to 18 carbon atoms as substrates, but it showed a higher affinity for acylcarnitines with longer carbon chains (Indiveri et al., 2011)

Carnitine, a naturally occurring compound synthesized in the liver and kidneys, plays a crucial role in energy metabolism by transporting fatty acids into mitochondria

SREBP1 primarily regulates fatty acid and triglyceride synthesis, whereas cholesterol biosynthesis is predominantly governed by SREBP2 (81)

E., Atwood, S