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Efficacy and safety of vixarelimab, a human monoclonal oncostatin M receptor B Antibody, in moderate-to-severe prurigo nodularis: A randomised, double-blind, placebo-controlled, phase 2a study

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Figure 2 2.2 Dynamic polarization and functional switch of macrophages Macrophages directly recognize pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) via surface pattern recognition receptors (PRRs) and opsonin receptors, internalizing them via receptor-mediated endocytosis

The field of proteomics has assisted in yielding better insight to the progression of injury, assessment of accurate diagnostic criteria for TBI, as well as the development of possible therapies for TBI