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doi: 10.1016/j.msec.2018.09.021

Spirulina is not a good source of B12 and only contains B12 analogues Because vitamin B12 is water-soluble it's extremely hard to overdose, and because the body is quite inefficient at absorbing B12, supplements often contain 10,000% RDA, sometimes even 100,000% RDA, to try and ensure the body actually absorbs some of it

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The cytosolic form of MDH is encoded by the MDH1 gene and the mitochondrial version is encoded by the MDH2 gene

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& Nedergaard, M