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Jan-Feb 1994;15(1):26-32

10.1038/srep15809 40 KirtikarK

The Therapeutic Potential of Anthocyanins: Current Approaches Based on Their Molecular Mechanism of Action

doi: 10.1155/2017/9074601

Although restricted to animal studies, the KD is related to several pathways in metabolic syndrome and cancer, including increased 5 adenosine monophosphate-activated protein kinase (AMPK) activity, inhibition of the mTOR/AKT pathway, 134 lowering the serum ratio of insulin-like growth factor/IGF-binding protein 3 135 and increasing peroxisome proliferator-activated receptor- coactivator-1 expression (a master mitochondrial metabolic regulator that can increase mitochondrial biogenesis)