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Glutathione S-Transferases

Briefly, HBMECs were seeded as mentioned above, while SH-SY5Y cells were seeded at 1 10 5 cells/well on the lower compartments of the Transwell insert for 24 h (Fig

Platinum(IV) complexes with non-cisplatin-like mechanisms of action Before it became established that most anticancer-active platinum(IV) complexes function as prodrugs that undergo reduction to release active platinum(II) agents, alternative mechanisms of action for platinum(IV) were envisioned

Interestingly, Glutathione is not only an antioxidant

Fumarate itself is a Michael acceptor, and the covalent attachment to protein cysteines corresponds to the post-translational modification known as succination [142] and fumarate has been recently demonstrated to yield a glutathione thioether in in vitro treated cells [142]

Endothelial cell senescence and age-related vascular diseases