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They act as biological response modifiers, activating or suppressing immunity in response to stimuli

Prescription agents (e.g., semaglutide) : Stronger clinical evidence, FDA-regulated, but may carry more systemic side effects

[4] Based on animal research, it is thought that the increased methylmalonyl-CoA hydrolyzes to form methylmalonate (methylmalonic acid), a neurotoxic dicarboxylic acid, causing neurological deterioration

A small number of pilot-scale investigations have been conducted, but large-scale randomized controlled trials have not been published

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