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Subsequently, the monocytes differentiate into macrophages that regulate various healing processes (Huang et al., 2020)

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Besides functioning as metabolic substrates which feed into hepatic glucose or lipid metabolism, SCFAs can also affect hepatic metabolism by serving as signaling molecules

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doi: 10.1016/j.clnu.2022.02.015

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Therefore, there is an attempt to induce methyl deficiency through feed additives, such as guanidinoacetic acid (GAA), to better evaluate the role of RPM in supporting methyl donor supply

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