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[DOI] [PubMed] [Google Scholar] 61.Zhu M., Lin Tay M., Lim K.S., Bolam S.M., Tuari D., Callon K., Dray M., Cornish J., Woodfield T.B.F., Munro J.T., et al

Treatment of persistent sleep-wake schedule disorders in adolescents with methylcobalamin (vitamin B12) The improvement of the sleep-wake rhythm disorders appeared immediately after the administration of high doses (3,000 micrograms/day) of methylcobalamin

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In my practice, I have found that there are clinical symptoms that can help identify those responders

Most healthy adults have a heavy store (up to several years worth) of B12 in their liver

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