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In order to compare the combined effect of metals and chelators in a comprehensive in vitro model, we engineered multidrug-resistant A431 cells overexpressing ABCB1/P-glycoprotein, ABCG2 or ABCC1/MRP1 (Fig S1, Fig S2, Fig S3)

and the increased levels of small chain fatty acids are also consistent 15, 38, 40

10.3389/fendo.2022.975724 131 LiuY.-C.WangJ.-W.LiJ.GuoY.HanF.-J.LuW.-H.et al (2024)

doi: 10.1161/01.CIR.77.4.787

119,120 As such, suppression of elastase and neutrophil activation may be helpful in hemorrhagic or thrombotic complications associated with COVID-19
