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For example, studies on the intestinal flora of patients with prehypertension and hypertension have found that the most significant characteristics are the reduction and uneven distribution of microbial diversity and abundance, mainly manifested in the increase of Firmicutes / Bacteroidetes ratio, the decrease of probiotics, and the increase of Prevotella and Klebsiella ( TMAO and CVDs Gut microbiota-derived metabolites, such as short-chain fatty acids, BAs, catechin, and TMAO, are the direct factors causing CVDs, and have been viewed as a new breakthrough for the prevention and treatment of CVDs (31)

Journal of Pediatrics 93: 959964, 1978 Welling PG, Thomsen JH, Shug AL, Tse FL

Immune function depends on multiple nutrients, highlighting the importance of a varied, nutrient-dense diet even during caloric restriction

ClmentKRuizJCassard-DoulcierAMBouillaudFRicquierDBasdevantAet al

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