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This activation, in turn, results in the degradation of the mutated form of tumor protein P53 (TP53), glyceraldehyde-3-phosphate dehydrogenase (GAPDH), an inhibitor of nuclear factor kappa B alpha (IB-), and HK2 protein, leading to metabolic catastrophe and cell death in AML cells [57, 58]

Michalak et al

J Mol Neurosci Bjrkman L, Lundekvam BF, Lgreid T, Bertelsen BI, Morild I, Lilleng P, Lind B, Palm B, Vahter M (2007) Mercury in human brain, blood, muscle and toenails in relation to exposure: An autopsy study

doi: 10.1146/annurev.biochem.74.082803.133329 92 ZhuJYamaneHPaulWE

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Shin DS, et al