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Without a modest calorie deficit, adequate protein, and regular movement, the fragment has far less to work with, because it influences how the body handles fat rather than forcing weight off on its own

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And any discussion about metabolism and growth, by definition has to include a discussion about growth hormones

Nat Rev Cancer 21(1):1832 Veith A, Henderson K et al (2019) Therapeutic strategies for enhancing angiogenesis in wound healing