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Dorszewska J, Oczkowska A, Suwalska M, Rozycka A, Florczak-Wyspianska J, Dezor M, Lianeri M, Jagodzinski PP, Kowalczyk MJ, Prendecki M, Kozubski W

1996 Jul;64(1):101-7

Yes, it can signal issues like ulcers or blockages that need a doctors check

References 1.Agerbirk N., Olsen C.E

It has been shown to reduce the activation of the MAPK/ERK and PI3K/Akt pathways, upregulate the cyclin-dependent kinase inhibitor p21, and trigger mitochondrial apoptosis by downregulating the anti-apoptotic proteins Bcl-2/Bcl-xL ( 3.1.4 Polyphenols: precision miRNA targeting for cancer suppression Curcumin emerges as a potent miRNA modulator with specific targeting of oncogenic and tumor suppressor miRNAs

Labra J, et al
