b12 1000 injection monthly dose CYANOCOBALAMIN INJECTION, USP 30000 mcg/30 mL (1000 mcg/mL) 30 mL VIAL Vitamin B12 Injection Dosage: 7

Overload on the kidneys or liver in patients with preexisting conditions

Status checked June 2026 Regulatory status can change

The strongest data comes from Harshini Neelakantan, Stan Watowich, and colleagues at the University of Texas Medical Branch (UTMB)

The National Institutes of Health recommend the following daily dosage of vitamin B12: Birth to 6 months: 0.4 micrograms Infants 712 months: 0.5 micrograms Children 13 years: 0.9 micrograms Children 48 years: 1.2 micrograms Children 913 years: 1.8 micrograms Teens 1418 years: 2.4 micrograms Adult men and women 1850 years: 2.4 micrograms Adult men and women over 50 years: 25250 micrograms Women who are pregnant: 2.6 micrograms Women who are breastfeeding: 2.8 micrograms Adults over the age of 50 are at a greater risk of vitamin B12 deficiency because they tend to produce less stomach acid, which is needed to convert the vitamin properly

Long-term storage of unreconstituted lyophilised powder should be at 20C or colder

Some clinicians have observed that younger adults may experience this side effect more frequently, though this has not been systematically studied