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Overall, this work aims at highlighting the critical role of kidney-insulin interplay in the development of dysmetabolism

Regulatory T cell (Treg) subsets return in patients with refractory lupus following stem cell transplantation, and TGF-beta-producing CD8+ Treg cells are associated with immunological remission of lupus

Jost HW, Kulisevsky J, LeWitt AP

[DOI] [PubMed] [Google Scholar] 123.Lu SC, Kuhlenkamp J, Garcia-Ruiz C, Kaplowitz NN

The decreased virulence of the sod1 strain may be due to increased susceptibility to oxygen radicals within macrophages, while other antioxidant defense systems in can compensate for the loss of Cu-Zn SOD in vivo [76]

The exact reasons for this cancellation remain undisclosed, leaving a massive void in baseline human safety data