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Contaminants, inaccurate labeling, and variable bioavailability are documented concerns within the supplement industry

10.1016/j.biomaterials.2016.09.007 157 van der MolenR

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97,200,207,208 CYP2C9 can generate all of these metabolites, but other CYPs are specific for hydroxylation at single positions

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Polyphenols may affect glycaemia through different mechanisms, including inhibition of intestinal glucose absorption, increasing glucose transport and metabolism in muscle and/or stimulating insulin secretion [217,219,243,244]
