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Curcumin triggers p16-dependent senescence in active breast cancer-associated fibroblasts and suppresses their paracrine procarcinogenic effects

In supplements appears to be well tolerated, but gastrointestinal side effects have been reported

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Those individuals interested in making formal oral presentations should notify the contact person and submit a brief statement of the general nature of the evidence or arguments they wish to present, the names and addresses of proposed participants, whether they would like to present online or in-person, and an indication of the approximate time requested to make their presentation on or before June 30, 2026

These hydrolytic enzymes are typically confined to lysosomal compartments, but like cathepsin B, they can be secreted by tumor cells in necrotic areas