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In 2015, a randomized clinical trial in laryngeal cancer, comparing radiotherapy with and without this combination, showed that this therapy decreased the risk of metastases (Rademakers 2015

Linaclotide for irritable bowel syndrome with constipation: a 26-week, randomized, double-blind, placebo-controlled trial

MBio 15:e0207524

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Interestingly, the patients who received the combined treatment experienced less overall improvement than those taking either form individually, suggesting that massive doses of competing carnitine forms might overwhelm cellular transport mechanisms

Liu H, Hu X, Li Z, Fa K, Gong H, Ma K, et al