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Superoxide dismutase reduces creatinine and NGAL by restoring oxidative balance during sepsis

Our results indicate that genetic impairment of both the thioredoxin and glutathione-dependent pathways can hinder the consumption of NADPH upon pro-oxidative challenges in the yeast cytosol, but the impact of blocking the glutathione pathway is more pronounced

[DOI] [PubMed] [Google Scholar] 170.Aqul A., Liu B., Ramirez C.M., Pieper A.A., Estill S.J., Burns D.K., Liu B., Repa J.J., Turley S.D., Dietschy J.M

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f , HeLa cells expressing the indicated Flag-tagged FL or truncated INTS12 proteins were untreated or treated with 4-NQO and then analyzed as in a

Zhu CH, Huang Y, Oberley LW, Domann FE