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Acknowledgments The writing of the manuscript was assisted by ChatGPT (OpenAI, California, US) and Grammarly (Superhuman Platform Inc., California, US) for language support

SFN can be diagnosed in patients with neuropathic symptoms by using quantitative sensory testing or quantitative sudomotor axon testing and by performing skin biopsies that show a decreased density of intraepidermal sensory nerve fibers within affected body regions

The World Anti-Doping Agency (WADA) prohibits AOD-9604 as a non-approved substance and potential performance-enhancing agent in athletics, citing concerns about unfair advantage through lean body mass gains (if efficacious, which remains unproven)

Epitalon activates telomerase to maintain telomere length and restores melatonin output