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Oxidative damage of lysosomes in regulated cell death systems: Pathophysiology and pharmacologic interventions

Other CRISPR studies have identified candidate susceptibility loci in detoxification pathways, including GSTM1, CYP1A1, and NQO1

This test detects NADPH production under UV light

Wu H, Guo H, Liu H, Cui H, Fang J, Zuo Z, et al

Genetic factors in chemically induced transitional cell bladder cancer

NRF2, a master regulator of antioxidant gene expression, translocates to the nucleus upon phosphorylation and activates downstream targets such as heme oxygenase-1 (HO-1), SOD, and quinone oxidoreductase-1 (NQO1) (316)