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All these are further modulated by the yet largely unknown influence of the environment

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The subject in need of treatment or prevention of a CNS disorder may be a vertebrate, mammal, or, preferably a human

Brain Behav Immun 26:11911201

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8B) as well as immunohistochemistry analysis of Ire1-induced Xbp1s expression following tunicamycin treatment (Tm, a glycosylation inhibitor to induce ER stress and activation of the Ire1-Xbp1s pathway in mouse tissue 30,31,32
