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Description
Overexpression of the active form of TGF-1 in mice induces lung fibrosis, and it is associated with downregulation of GCL gene expression, decreased GSH levels in BALF, and increased oxidative stress (Liu et al., 2012)

doi: 10.1039/C8NA00255J

White, Andrea T

[DOI] [PubMed] [Google Scholar] [120].Jacob S, Streeper RS, Fogt DL, Hokama JY, Tritschler HJ, Dietze GJ, Henriksen EJ

Front Plant Sci 07
Results and Discussion Metabolic Stability in vitro It is known that liver metabolism, especially CYP450 enzymes, contributes much to drug clearance and is considered one of the crucial factors for the systematic drug exposure, which was why the metabolic stability of ASD in rat liver microsomes was the first to be evaluated