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La L-Carnitina libre, con su carga positiva cuaternaria permanente y alta polaridad, no tiene transportadores funcionales en el endotelio cerebral a concentraciones suplementarias

& Findlay, J

Hu X, Xia M, Wang J, Yu H, Chai J, Zhang Z, et al

Carnitine, Acylcarnitines and Fatty Acid Transport into Mitochondria The substrates for oxidation and most of the energy production in cells are unesterified fatty acids, which originate from three main sources: exogenous fatty acids that enter cells from the circulation, either from the diet or by mobilization from other tissues, those that arise via synthesis de novo from acetyl-CoA, and those released within the cell by the hydrolysis of phospholipids and triacylglycerols

However, higher doses were used in most of the studies discussed in this article

Isolation and characterization of microorganisms involved in l-carnitine catabolism