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In a cerebral ischemia rat model, Lin et al (206) observed that serum glucose-oxygen deprivation significantly increases microglial LD accumulation, concurrent with elevated release of inflammatory mediators TNF- and IL-1

doi: 10.1038/ni.2262 127 HuangHYRivas-CaicedoAReneveyFCannelleHPeranzoniEScarpellinoLet al

For each sample, thin sections were cut using a Leica EM UC7 ultramicrotome (Leica Microsystems)

SAM also serves as a methyl donor for multiple methylation reactions catalyzed by methyltransferases (MTs) specific for RNA, DNA, histones, and proteins [31]

doi: 10.1021/bc5005262

An analog of taurocholic acid, tauroursodeoxycholic acid (TUDCA), is a naturally occurring bile acid and is a conjugate of taurine and ursodeoxycholic acid (UDCA)