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Copper induces oxidative stress and H 2 O 2 production in HepG2 ATP7B-KO cells After 6 h of CuCl treatment, chosen oxidative stress-related genes were significantly upregulated in HepG2 ATP7B-KO cells, while only HMOX1 showed early induction in HepG2 cells

The association between fatty acid index and in vitro fertilization outcomes

Hoang, G., Udupa, S., & Le, A

[DOI] [PubMed] [Google Scholar] 61.Grochocka M, Weniak A, Biaczyk A, Marek-Jozefowicz L, Tadrowski T, Czajkowski R

These mitochondrial morphological alterationsincluding reduced organelle size, increased membrane density, and cristae disruptionare established ultrastructural hallmarks of ferroptosis and are functionally associated with impaired mitochondrial bioenergetics, including loss of membrane potential, diminished electron transport chain activity, and excessive ROS generation (Figure 2G)