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Hepatic and renal contributions to valproic acid-induced hyperammonemia

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A shunt surgery was done, to relieve the symptoms of intracranial hypertension, followed by MRI and/or computed tomography (CT) assessment every 3 months

This process involves the sequestration and degradation of cellular components in a double-membrane structure called the autophagosome, which fuses with lysosomes leading to the degradation of the aggregates (Takahashi et al